HPE P50311-B21 — 32GB DDR5-4800 EC8 Registered Smart Memory for AMD ProLiant Gen11
32GB DDR5 RDIMM4800 MT/s · CAS 40Dual rank x8 · EC8AMD EPYC 9004 Gen11
The HPE P50311-B21 is the genuine HPE 32GB (1x32GB) Dual Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory Kit for HPE ProLiant Gen11 servers with 4th Gen AMD EPYC (9004) processors, such as the DL325, DL345 and DL385 Gen11.
HPE lists it among the 4800 MT/s DIMMs supported on 4th Gen AMD EPYC processors. HPE Smart Memory is qualified and tuned for ProLiant, is recognised by iLO as genuine HPE memory, and supports HPE's Advanced ECC memory protection. Use it to expand or replace memory in an AMD Gen11 host while keeping an all-HPE configuration for support.
Before you order: HPE does not support mixing x4 and x8 DIMMs, or 3DS and non-3DS DIMMs, in the same server. This is a dual rank x8 module — if your server already has x4 modules (for example 64GB 2Rx4), choose a matching x4 kit instead. Servers with 5th Gen AMD EPYC (9005) use the DDR5-6400 kits.
What's in the Box
- 1 × HPE 32GB DDR5-4800 EC8 Registered DIMM (P50311-B21 kit)
- HPE option-kit packaging — no tools or software required
What It Means in Practice
- Maximum memory speed is set by the processor and population rules in the server QuickSpecs; 4800 MT/s is the 4th Gen EPYC native speed.
- EPYC 9004 has 12 memory channels per socket — populating all 12 with identical modules gives the full bandwidth these CPUs are designed for.
- Smart Memory is reported in iLO as HPE memory, which keeps support cases simple.
- Keep every module in the server the same organisation (x8) and type (non-3DS RDIMM).
What Will Not Work
- Intel-based ProLiant Gen11 systems unless their QuickSpecs list this kit — check before ordering
- Servers already using x4 or 3DS DDR5 modules — mixing is not supported
- Gen10/Gen10 Plus DDR4 servers and any desktop or workstation using unbuffered memory
- ProLiant ML30/DL20/MicroServer Gen11, which take ECC UDIMMs only
Key Features
DDR5-4800 RDIMM
32GB dual rank x8 Registered module with CAS 40-39-39.
EC8 ECC
DDR5 error correction with HPE Advanced ECC support on ProLiant.
HPE Smart Memory
Qualified for ProLiant and identified by iLO as genuine HPE memory.
AMD Gen11
Listed for DL325, DL345 and DL385 Gen11 with 4th Gen AMD EPYC.
Technical Specifications
| Identification |
| Part Number |
P50311-B21 |
| EAN / GTIN |
0190017566597 |
| Brand |
HPE |
| Memory |
| Capacity |
32GB (1 × 32GB) |
| Type |
DDR5 EC8 Registered DIMM (RDIMM), HPE Smart Memory |
| Speed |
4800 MT/s (set by CPU and population) |
| CAS latency |
40-39-39 |
| Rank / organisation |
Dual rank x8 |
| Pins |
288-pin |
| Compatibility |
| Supported servers |
HPE ProLiant DL325 Gen11, DL345 Gen11, DL385 Gen11 (4th Gen AMD EPYC 9004) |
| Mixing rules |
No x4/x8 mixing · no 3DS/non-3DS mixing |
| Warranty |
| Warranty |
1-Year Warranty (Singular) |
| Manufacturer Term |
Separate memory-kit term not published by HPE; supported under the HPE server warranty — claims handled through Singular |
Frequently Asked Questions
Why not use a cheaper generic DDR5 RDIMM?
Generic modules often work, but iLO flags non-HPE memory and HPE support may ask for HPE parts. Smart Memory keeps the server fully supported.
How many should I install?
For full bandwidth, one identical module in each of the 12 channels per EPYC 9004 socket. Fewer DIMMs work, but follow the population order in the QuickSpecs.
Does it work with 5th Gen EPYC (9005)?
HPE lists the DDR5-6400 kits for 5th Gen EPYC. Ask us and we will confirm the right kit for your CPU.
Singular Expert Insight · Buyer's Guide
With 12 channels per socket, AMD Gen11 servers reward fully populated, identical memory — 32GB dual-rank x8 modules are a common balanced choice for virtualisation hosts. Browse our
memory (RAM) range for other capacities and server modules.
✓ Buy it if you run a ProLiant DL325, DL345 or DL385 Gen11 with 4th Gen EPYC and use x8 RDIMMs.
✕ Skip it if your server has x4 or 3DS modules installed, uses 5th Gen EPYC, or is an Intel Gen11 model not listed for this kit.
→ Also consider HPE P64336-B21 (16GB ECC UDIMM) for ProLiant ML30/DL20/MicroServer Gen11.
Not sure it fits your server? Send us the ProLiant model, CPU and installed memory and we will check before you order.