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Lenovo ThinkPad E16 Gen 4 16-inch WUXGA Laptop AMD Ryzen AI 5 330 16GB DDR5 512GB SSD Windows 11 Pro

Brand:
Lenovo
LENOVO NOTEBOOK THINKPAD E16 G4, AMD RYZEN AI 5 330, 16GB, 512GB SSD, AMD RADEON 820M, 16'
Lenovo ThinkPad E16 Gen 4 16-inch WUXGA Laptop AMD Ryzen AI 5 330 16GB DDR5 512GB SSD Windows 11 Pro
€1445.79 inc. VAT
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21Y4003UVU
€1,214.95 €1,349.95
€1,445.79 inc. VAT
Ships from EU stock: 6 item(s)
CPU Type
AMD Ryzen
Product Code
09:21Y4003UVU
EAN Code
0199275769511
Manufacturer
Lenovo

Quick Specs

Processor
AMD Ryzen AI 5 330, 4C / 8T
AI
Copilot+ PC, 50 TOPS neural engine
Memory
16GB DDR5, second slot free, 64GB max
Storage
512GB NVMe, M.2 2280 slot free
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Lenovo ThinkPad E16 Gen 4 — A 50 TOPS Copilot+ Engine and Two Slots for Everything

Copilot+ PC — 50 TOPS AMD Ryzen AI engineTwo SODIMM slots, upgradable to 64GBTwo M.2 slots and Wi-Fi 7Aluminium body, 16-inch screen, 1.63 kg

The Lenovo ThinkPad E16 Gen 4 is the 16-inch AMD model of the E Series, and its neural engine is the strongest in the current range — AMD Ryzen AI rated at up to 50 TOPS, comfortably past the Copilot+ threshold. It ships with 16GB of DDR5 in one of two slots and a 512GB NVMe drive in one of two M.2 slots, so both memory and storage can be added to later. The body is aluminium top and bottom at 1.63 kg, the battery is 64 Wh, and the port list keeps two USB4 sockets, gigabit ethernet, two USB-A and full-size HDMI.

Compatibility — check before buying:
This is a 4-core processor. The Ryzen AI 5 330 has four cores and eight threads — fewer than any Intel model in this range, which run six or eight. Its strength is the 50 TOPS neural engine and battery efficiency, not parallel throughput; if you compile, encode or render, an 8-core machine will be quicker. The USB-C ports are USB4, not Thunderbolt, and carry DisplayPort 1.4a rather than 2.1 — docking works, but check any Thunderbolt-certified dock with us first. The panel is 45% NTSC: bright and matte at 400 nits with AICCP colour calibration applied, but a narrow gamut regardless. Each M.2 slot is capped at 1TB. There is no smart card reader, no SD reader and no mobile broadband. Lenovo lists the machine as Non-DASH, the AMD equivalent of Non-vPro, so it is outside out-of-band fleet management.

Best For

✓ On-device AI work that uses the 50 TOPS neural engine
✓ Fleet deployments that will add memory or storage later
✓ Spreadsheet and multi-window work on a 16-inch screen
✓ Offices with wired ethernet at the desk
✓ Long days on the 64 Wh battery with an efficient 4-core chip
✓ Deployments wanting three years of onsite cover

Key Features

 
The strongest neural engine here
AMD Ryzen AI rated at up to 50 TOPS — higher than the 47 TOPS Intel parts and well past the 40 TOPS Copilot+ threshold. On-device AI features run locally rather than in the cloud.
 
Two slots for memory, two for storage
One of the two DDR5-5600 SODIMM slots is free, taking the machine to 64GB by adding a module. The fitted 512GB drive sits in the M.2 2242 slot, leaving a 2280 slot open for a second SSD of up to 1TB.
 
Aluminium, and light for 16 inches
Anodised aluminium top and bottom, MIL-STD-810H tested, at 1.63 kg — lighter than the 1.7 kg ThinkBook 16 models and well under the 1.85 kg ThinkPad L16.
 
A full port list and Wi-Fi 7
Two USB4 ports at 40 Gbps with 15–65 W power delivery, two USB-A, HDMI 2.1 at 4K/60, gigabit ethernet and a combo jack, with 802.11be Wi-Fi 7 and Bluetooth 5.4.

Technical Specifications

Identification
Brand Lenovo
Series ThinkPad E Series
Model ThinkPad E16 Gen 4 (AMD)
Part Number 21Y4003UVU
Machine Type 21Y4
EAN / GTIN 0199275769511 (published by Lenovo PSREF)
Region EET — Cyprus
Announced 17 May 2026
End of Support 20 December 2032
Processor and Memory
Processor AMD Ryzen AI 5 330 — 4 cores, 8 threads, 2.0 GHz base to 4.5 GHz, 4 MB L2 and 8 MB L3 cache
AI Category Copilot+ PC
NPU AMD Ryzen AI, up to 50 TOPS
Graphics Integrated AMD Radeon 820M
Memory Fitted 1x 16GB SODIMM DDR5-5600
Memory Slots Two DDR5 SODIMM slots, dual-channel capable — one free
Maximum Memory 64GB DDR5-5600
System Management Non-DASH
Storage and Display
Drive Fitted 512GB SSD, M.2 2242, PCIe 4.0 x4 NVMe, Opal 2.0
Storage Slots Two M.2 slots — one 2242 and one 2280, both PCIe 4.0 x4
Maximum Storage Two drives, up to 1TB each
Card Reader None
Display 16-inch WUXGA 1920x1200 IPS, 400 nits, anti-glare, 45% NTSC, 60 Hz
Colour Calibration AICCP colour calibration
Touchscreen No; pen not supported
Screen-to-Body Ratio 90.7%
Audio, Camera and Battery
Camera FHD 1080p with IR, hybrid, physical privacy shutter
Microphone 2x array
Speakers Stereo, 2 W x2, Dolby Atmos, audio by HARMAN
Audio Codec High Definition Audio, Senary SN6147
Battery 64 Wh
Power Adapter 65 W USB-C, 3-pin
Connectivity
Wireless Wi-Fi 7, 802.11be 2x2, Bluetooth 5.4
Ethernet 100/1000M RJ-45
Mobile Broadband Not supported
USB-C 2x USB4 40 Gbps with USB PD 15–65 W and DisplayPort 1.4a — USB4, not Thunderbolt
USB-A 1x USB-A 5 Gbps; 1x USB-A 10 Gbps, Always On
Video Out 1x HDMI 2.1, up to 4K at 60 Hz
Audio Jack 1x 3.5 mm headphone and microphone combo
NFC No
Docking USB-C docking solutions supported
Build and Security
Case Material Aluminium, top and bottom
Colour Black
Dimensions 356 x 249 x 10.1–17.05 mm (front to rear), 21.15 mm maximum
Weight From 1.63 kg
Keyboard Backlit, English (EU) layout
Security Chip Discrete TPM 2.0, enabled
Fingerprint Reader Touch style, match-on-chip, integrated in the power button
Facial Recognition IR camera for Windows Hello
Smart Card Reader None
Privacy Camera privacy shutter
Physical Lock Kensington Nano Security Slot, 2.5 x 6 mm
Durability MIL-STD-810H military test passed
Software, Certifications and Warranty
Operating System Windows 11 Pro, English (US) / English (UK)
Bundled Software None
Certifications ENERGY STAR 9.0, EPEAT 2.0 Gold registered, ErP Lot 6/26, RoHS compliant, TCO Certified generation 10, TÜV Rheinland Low Blue Light (software solution)
Warranty 1-Year Warranty (Singular)
Manufacturer Term Lenovo publishes a 1-year courier or carry-in base warranty on this model, with a 3-year onsite upgrade included in this part number. Singular’s direct warranty is 1 year; beyond that we assist you with the manufacturer’s warranty process for its full duration.
In the Box Notebook and 65 W USB-C power adapter. Lenovo lists no bundled accessories beyond these.

Frequently Asked Questions

Four cores sounds low. Is it fast enough?
For office work, browsing, email and on-device AI, yes — and the 50 TOPS neural engine is the strongest in this range. For compiling, video encoding or rendering, the eight-core Intel models will be noticeably quicker. Tell us what the machine will actually run and we will match it properly.
Is USB4 the same as Thunderbolt?
Close, but not identical. Both USB-C ports run at 40 Gbps with 15–65 W power delivery and drive displays over DisplayPort 1.4a, so most USB-C docks work. Thunderbolt certification and DisplayPort 2.1 are not published for this model, so check any specific Thunderbolt dock with us first.
Can I upgrade the memory and add a second drive?
Both. One of the two SODIMM slots is free, so 64GB is reached by adding a module rather than replacing. The fitted 512GB drive occupies the M.2 2242 slot, leaving the 2280 slot open for a second SSD of up to 1TB.
What does Non-DASH mean?
DASH is AMD’s out-of-band management standard, the equivalent of Intel vPro. Non-DASH means this machine cannot be managed below the operating system by DASH-based fleet tools. If that is a requirement, tell us and we will find a model that supports it.
Singular Expert Insight
This is an unusual machine to place. It has the strongest neural engine in the whole range at 50 TOPS, the same expandability as the best E14 — two memory slots to 64GB and two drive slots — and it is lighter than any other 16-inch here at 1.63 kg. But it runs on four cores, which is half what the Intel E14 Gen 8 Panther Lake model offers, and its USB-C ports are USB4 rather than Thunderbolt. Read that as a machine built for efficiency and AI rather than throughput: excellent for a mobile office user who wants a big screen, a long battery and room to upgrade; the wrong choice for anyone whose work is genuinely processor-bound. Buy on the workload, not the TOPS figure. Memory is in our DDR5 SODIMM range and docks in our docking station range.

Buyer’s Guide

Buy it if

You want a light 16-inch ThinkPad with the strongest on-device AI engine here, room to reach 64GB and two drives, ethernet and Wi-Fi 7, for office work rather than heavy computation.

Skip it if

Your work is processor-bound and would use six or eight cores, you need certified Thunderbolt docking, or your policy requires DASH management, a smart card reader or colour accuracy.

Also consider

ThinkPad E14 Gen 8 machine type 21Y6 for an 8-core Intel processor with Thunderbolt 4 and the same expandability, at 14 inches. ThinkPad L16 Gen 3 for a 16-inch machine with a smart card reader. ThinkBook 16 G8 for a 71 Wh battery and fourteen cores.

Features - Lenovo - 21Y4003UVU

Colour
black
More Details
Product Code
09:21Y4003UVU
EAN Code
0199275769511
Manufacturer
Lenovo
Technical specifications
Monitor Size
16"
CPU Type
  • AMD Ryzen
Memory Size
  • 16GB
Capacity
512GB
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